Description

2,4-Dichloro-5,6,7,8-tetrahydroquinazoline is a versatile heterocyclic building block and key synthetic intermediate with significant value in advanced organic synthesis. Its unique fused ring structure, featuring both a tetrahydroquinoline and a chlorinated pyrimidine moiety, makes it a critical precursor for the development of complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a core scaffold for the synthesis of potential drug candidates, particularly in medicinal chemistry research targeting various therapeutic areas.
• Agrochemical Synthesis: Used as a key building block in the development of new herbicides, fungicides, and insecticides, leveraging its chlorinated heterocyclic structure.
• Organic Light-Emitting Diodes (OLEDs): Acts as a precursor for electron-transport materials or host materials in the fabrication of advanced OLED displays and lighting.
• Ligand and Catalyst Development: Employed in the preparation of novel nitrogen-containing ligands for transition metal catalysis and coordination chemistry.
• Material Science Research: Utilized in the synthesis of specialty polymers and advanced organic materials with specific electronic or photophysical properties.
• Chemical Research & Development: A valuable reagent for exploring new heterocyclic chemistry and constructing complex molecular architectures in academic and industrial R&D labs.

Basic Information

Product Name	2,4-Dichloro-5,6,7,8-tetrahydroquinazoline
CAS No.	1127-85-1
Molecular Formula	C8H8Cl2N2
Molecular Weight	203.07 g/mol
Synonyms	2,4-Dichloro-5,6,7,8-tetrahydroquinazoline; 5,6,7,8-Tetrahydro-2,4-dichloroquinazoline; 2,4-Dichloro-5,6,7,8-tetrahydro-benzo[d]pyrimidine; 2,4-Dichloro-5,6,7,8-tetrahydroquinazoline; Tetrahydro-2,4-dichloroquinazoline; Benzo[d]pyrimidine, 2,4-dichloro-5,6,7,8-tetrahydro-; 1127-85-1 (CAS)
EINECS	Contact for details

Quality Control

Our 2,4-Dichloro-5,6,7,8-tetrahydroquinazoline is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent chemical identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.