Description

1-Methylhypoxanthine is a purine derivative and a methylated analog of hypoxanthine, a key intermediate in nucleotide metabolism. This compound is of significant interest in biochemical research and pharmaceutical development due to its role as a potential metabolite and reference standard. It serves as a critical building block and analytical standard for researchers and manufacturers in the life sciences sector, particularly those focused on nucleotide chemistry, metabolic pathway studies, and drug discovery.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor or metabolite in the development of nucleoside-based drugs and antiviral agents.
• Biochemical Research: Used as a reference standard or substrate in enzymatic studies, particularly those involving purine metabolism, methyltransferases, and nucleotide salvage pathways.
• Life Science Reagents: Incorporated into specialized cell culture media or diagnostic assay kits for studying cellular metabolism and nucleotide turnover.
• Analytical Chemistry: Employed as a high-purity certified reference material (CRM) for method development and quality control in HPLC, LC-MS, and other analytical techniques.
• Academic Research: Utilized in universities and research institutes for fundamental studies in biochemistry, molecular biology, and medicinal chemistry.

Basic Information

Product Name	1-Methylhypoxanthine
CAS No.	1125-39-9
Molecular Formula	C6H6N4O
Molecular Weight	150.14 g/mol
Synonyms	1-Methyl-1H-purin-6(9H)-one; 1-Methyl-6-oxopurine; N1-Methylhypoxanthine; 6-Hydroxy-1-methylpurine; Hypoxanthine, 1-methyl-; 1-MHX
EINECS	214-413-7

Quality Control

Our 1-Methylhypoxanthine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including identity confirmation by IR and NMR, purity assessment by HPLC, and control of related substances and residual solvents. We provide full traceability and Certificates of Analysis (COA) are available for all shipments to ensure compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.