Description

4-Iodo-2-(Methylthio)Pyrimidine is a high-value halogenated pyrimidine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both iodine and a methylthio group, makes it an essential intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of nucleoside analogs, antiviral agents, and kinase inhibitors.
• Agrochemical Research: Used in developing new herbicides, fungicides, and plant growth regulators.
• Material Science: Building block for creating functionalized ligands in catalysis and organic electronic materials.
• Chemical Synthesis: Versatile substrate for cross-coupling reactions (e.g., Suzuki, Sonogashira) and nucleophilic substitution reactions.
• Bioconjugation: Potential reagent for modifying biomolecules due to the reactive iodo group.
• Academic & R&D: Fundamental research tool in medicinal chemistry and heterocyclic compound development.

Basic Information

Product Name	4-Iodo-2-(Methylthio)Pyrimidine
CAS No.	1122-74-3
Molecular Formula	C5H5IN2S
Molecular Weight	252.08 g/mol
Synonyms	2-(Methylthio)-4-iodopyrimidine; 4-Iodo-2-methylsulfanylpyrimidine; 4-Iodo-2-(methylmercapto)pyrimidine; Pyrimidine, 4-iodo-2-(methylthio)-; 4-Iodo-2-methylthiopyrimidine
EINECS	Contact for details

Quality Control

Our 4-Iodo-2-(Methylthio)Pyrimidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) documenting purity, appearance, and specific impurities are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling should be minimized under direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.