Description

Dansyl-L-Isoleucine is a high-purity, fluorescently labeled derivative of the essential amino acid L-Isoleucine. This compound is critical for advanced biochemical research and analytical applications, offering a reliable and sensitive probe for protein and peptide studies. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and diagnostic kit manufacturers requiring precise molecular tagging and detection.

Application

• Fluorescent Labeling Agent: Used as a sensitive derivatization reagent for the HPLC analysis of amino acids, peptides, and proteins.
• Biochemical Research: Serves as a critical tool in studying protein structure, function, and protein-protein interactions via fluorescence techniques.
• Pharmaceutical Development: Employed in the R&D of new therapeutic agents and in pharmacokinetic studies to track drug metabolism.
• Diagnostic Assays: Integrated into the development of high-sensitivity fluorescent immunoassays and other clinical diagnostic tests.
• Proteomics & Metabolomics: Facilitates the identification and quantification of biomolecules in complex biological samples.
• Quality Control Testing: Acts as a reference standard in pharmaceutical quality control laboratories for method validation and compliance.

Basic Information

Product Name	Dansyl-L-Isoleucine
CAS No.	1100-21-6
Molecular Formula	C18H26N2O4S
Molecular Weight	366.48 g/mol
Synonyms	5-(Dimethylamino)naphthalene-1-sulfonyl-L-isoleucine; Dansyl-L-Ile; Nε-Dansyl-L-isoleucine; L-Isoleucine, N-[5-(dimethylamino)-1-naphthalenesulfonyl]-; DNS-Ile; 1-Dimethylaminonaphthalene-5-sulfonyl-L-isoleucine; N-Dansyl-L-isoleucine
EINECS	214-150-6

Quality Control

Our Dansyl-L-Isoleucine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and spectroscopic identification, to ensure it meets the stringent requirements for research and analytical applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Optical Rotation	-20° to -30° (c=1 in methanol)
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.