Description

n-Formylkynurenine is a key intermediate metabolite in the tryptophan degradation pathway, specifically in the kynurenine pathway. This compound is of significant interest in biochemical research and pharmaceutical development due to its role in cellular metabolism and immune system modulation. It is primarily utilized by research institutions, pharmaceutical companies, and diagnostic manufacturers for studying neurological disorders, inflammatory responses, and developing novel therapeutic agents.

Application

• Biochemical Research: Critical intermediate for studying the kynurenine pathway and its implications in neurodegenerative diseases like Alzheimer's and Parkinson's.
• Pharmaceutical Development: Used as a reference standard and building block in the synthesis of compounds targeting immune modulation and neurological conditions.
• Diagnostic Reagent Manufacturing: Serves as a calibrant or component in assay kits designed to measure tryptophan metabolism biomarkers in biological samples.
• Metabolomics Studies: Employed as a standard in mass spectrometry and chromatography for the quantitative analysis of metabolic pathways in cell culture and tissue samples.
• Enzymology Studies: Substrate for enzymes like kynurenine formamidase, used to study enzyme kinetics and inhibitor screening.

Basic Information

Product Name	n-Formylkynurenine
CAS No.	1022-31-7
Molecular Formula	C11H12N2O4
Molecular Weight	236.22 g/mol
Synonyms	N-Formylkynurenine; Nα-Formyl-L-kynurenine; L-Nα-Formylkynurenine; 2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid; Formylkynurenine; Kynurenine, N-formyl-; (2S)-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid
EINECS	213-818-7

Quality Control

Our n-Formylkynurenine is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant quality guidelines to support our clients in pharmaceutical and advanced research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing at -20°C under inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.