Description

(R)-3-Amino-2-Phenyl-Propionic Acid CAS NO 1008-63-5 is a high-purity, non-natural chiral amino acid derivative, specifically the (R)-enantiomer of 3-amino-2-phenylpropionic acid. This compound is a critical chiral building block and intermediate in the synthesis of complex pharmaceutical molecules, enabling the development of enantiomerically pure drugs with targeted biological activity. It is essential for research and production in the pharmaceutical, biotechnology, and fine chemical industries, particularly for applications in peptidomimetics, enzyme inhibitors, and active pharmaceutical ingredient (API) development.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure Active Pharmaceutical Ingredients (APIs), especially in cardiovascular and central nervous system (CNS) drug candidates.
• Peptidomimetics & Drug Design: Used to construct peptide analogs and mimetics with enhanced metabolic stability and receptor selectivity for novel therapeutic agents.
• Enzyme Inhibitor Development: Serves as a core structural component in the design and synthesis of potent, selective enzyme inhibitors for biochemical research and drug discovery.
• Asymmetric Synthesis: Employed as a chiral auxiliary or starting material in asymmetric catalytic reactions to introduce stereogenic centers in complex organic molecules.
• Bioconjugation & Linker Chemistry: Utilized in the preparation of bioconjugates, antibody-drug conjugates (ADCs), and specialized linkers due to its amino and carboxylic acid functional groups.
• Fine Chemical & Custom Synthesis: A valuable intermediate for custom synthesis and manufacturing services requiring high optical purity and consistent quality.

Basic Information

Product Name	(R)-3-Amino-2-Phenyl-Propionic Acid
CAS No.	1008-63-5
Molecular Formula	C9H11NO2
Molecular Weight	165.19 g/mol
Synonyms	(R)-3-Amino-2-phenylpropanoic acid; (R)-2-Phenyl-β-alanine; (R)-β-Homophenylalanine; (R)-3-Amino-2-phenylpropionic acid; D-3-Amino-2-phenylpropionic acid; (R)-2-Amino-3-phenylpropanoic acid isomer; (R)-3-Amino-2-phenylpropanoate; (R)-β-Phenyl-β-alanine
EINECS	Contact for details

Quality Control

Our (R)-3-Amino-2-Phenyl-Propionic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with stringent specifications for pharmaceutical and research applications. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.