Description

L-Histidine Hydrochloride is the hydrochloride salt form of the essential amino acid L-Histidine, a critical building block for proteins and enzymes. This high-purity compound is vital for applications demanding precise biochemical activity and stability, such as cell culture media and pharmaceutical formulations. It serves as a key raw material for manufacturers in the pharmaceutical, nutraceutical, and research sectors who require reliable, high-quality amino acid derivatives for their processes.

Application

• Pharmaceutical Intermediates: Used in the synthesis of active pharmaceutical ingredients (APIs) and peptide drugs.
• Cell Culture & Fermentation Media: An essential nutrient component in media for mammalian cell culture and microbial fermentation processes.
• Dietary Supplements & Clinical Nutrition: Incorporated into amino acid infusion solutions, enteral/parenteral nutrition, and specialty dietary supplements.
• Biochemical Research: Serves as a standard, reagent, or buffer component in enzymatic studies and protein research.
• Cosmetic & Personal Care: Utilized in formulations for skin and hair care products for its moisturizing and conditioning properties.

Basic Information

Product Name	L-Histidine Hydrochloride
CAS No.	1007-42-7
Molecular Formula	C6H10ClN3O2
Molecular Weight	191.62 g/mol
Synonyms	L-Histidine HCl; Histidine Hydrochloride; (S)-2-Amino-3-(1H-imidazol-4-yl)propanoic acid hydrochloride; Histidine Monohydrochloride; H-His-OH·HCl; L-Histidine, hydrochloride; L-Histidine HCl monohydrate (for hydrated form); Histidine hydrochloride
EINECS	213-747-3

Quality Control

Our L-Histidine Hydrochloride is manufactured under strict quality management systems. It is subjected to rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets high-grade specifications suitable for pharmaceutical and research applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed immediately after use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	≥98.5%
Specific Rotation	+8.5° to +10.5° (c=2 in 6N HCl)
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤10 ppm
Chloride Content	17.0% - 18.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.