Description

Homoarginine CAS NO 156-86-5 is a non-proteinogenic amino acid analog of L-arginine, characterized by an additional methylene group in its side chain. This structural modification makes it a valuable biochemical tool and a compound of significant interest in metabolic and cardiovascular research. It is primarily utilized by research institutions, pharmaceutical developers, and manufacturers of high-purity biochemical reagents. Its role as a substrate and inhibitor for nitric oxide synthase (NOS) enzymes underpins its importance in studying vascular function and cellular signaling pathways.

Application

• Biochemical Research: Used as a specific substrate for nitric oxide synthase (NOS) enzymes to study NO production and related vascular physiology.
• Pharmaceutical Intermediates: Serves as a key chiral building block or precursor in the synthesis of novel therapeutic compounds and peptide analogs.
• Diagnostic Reagents: Incorporated into assay kits and calibrators for the clinical measurement of related amino acids or enzyme activity in biological samples.
• Nutritional Science Studies: Investigated for its potential metabolic effects and interactions with arginine metabolism pathways.
• Cell Culture & Microbiology: Employed in specialized cell culture media formulations to study amino acid transport and metabolism.
• Reference Standards: Supplied as a high-purity certified reference material (CRM) for analytical method development and quality control in laboratories.

Basic Information

Product Name	Homoarginine
CAS No.	156-86-5
Molecular Formula	C7H16N4O2
Molecular Weight	188.23 g/mol
Synonyms	L-Homoarginine; (S)-2-Amino-6-(diaminomethylideneamino)hexanoic acid; Homo-L-arginine; NG-(Aminoiminomethyl)-L-lysine; 2-Amino-6-guanidinohexanoic acid; 6-Guanidino-2-aminohexanoic acid; HArg; hArg
EINECS	205-865-1

Quality Control

Our Homoarginine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identification by IR and NMR, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We can supply material compliant with various internal specifications and support custom purity requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); ensure the container is kept sealed in a dry environment to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]D20	+23.0° to +26.0° (c=1 in 1N HCl)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤10 ppm
Chiral Purity (HPLC)	≥99.0% L-isomer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.