Description

5-Fluoro-1-Methyl-Cytosine is a fluorinated pyrimidine nucleobase analog, a key building block in medicinal chemistry and advanced material science. Its value lies in its role as a versatile intermediate for synthesizing modified oligonucleotides and novel pharmaceutical agents, particularly in antiviral and anticancer research. This high-purity compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and agrochemical industries who require precise molecular modifications for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel nucleoside analogs with potential antiviral and antitumor activities.
• Antisense Oligonucleotide (ASO) Research: Used to incorporate modified bases into oligonucleotides to enhance stability, binding affinity, and specificity for therapeutic applications.
• Prodrug Development: Serves as a precursor in the design and synthesis of prodrugs aimed at improving bioavailability and targeted delivery.
• Biochemical Research: Employed in enzymatic studies and as a substrate analog to investigate nucleic acid metabolism and related biological pathways.
• Agrochemical Synthesis: Intermediate in the development of new agrochemicals, such as herbicides or plant growth regulators, that utilize fluorinated pyrimidine structures.
• Material Science: Potential monomer for creating specialized polymers or coatings with unique electronic or structural properties.

Basic Information

Product Name	5-Fluoro-1-Methyl-Cytosine
CAS No.	155-15-7
Molecular Formula	C5H6FN3O
Molecular Weight	143.12 g/mol
Synonyms	1-Methyl-5-fluorocytosine; 5-Fluoro-1-methylcytosine; 5-Fluoro-1-methyl-4-aminopyrimidin-2(1H)-one; 4-Amino-5-fluoro-1-methyl-2(1H)-pyrimidinone; 5-F-1-Me-Cyt; 5-Fluoro-1-methyl-cytosin; 5-Fluorocytosine, 1-methyl-; 1-Methyl-5-fluoro-cytosine
EINECS	Contact for details

Quality Control

Our 5-Fluoro-1-Methyl-Cytosine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.