Description

2,4-Pyrimidinediamine, 5-Fluoro- (9Ci) is a high-purity fluorinated pyrimidine derivative, serving as a critical building block in advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for its structural utility in creating novel compounds.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of antiviral and anticancer drug candidates, particularly those targeting nucleotide metabolism.
• Agrochemical Research: Used in the development of novel herbicides and fungicides that leverage its fluorinated pyrimidine core for enhanced biological activity.
• Biochemical Research: Serves as a precursor for labeled compounds or probes used in metabolic pathway studies and enzyme inhibition assays.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing specialized fluorinated heterocyclic compounds.
• Material Science: Investigated as a monomer or additive for creating specialty polymers with unique electronic or optical properties.

Basic Information

Product Name	2,4-Pyrimidinediamine, 5-Fluoro- (9Ci)
CAS No.	155-11-3
Molecular Formula	C4H5FN4
Molecular Weight	128.11 g/mol
Synonyms	5-Fluoro-2,4-pyrimidinediamine; 5-Fluorocytosine; 5-FC; 4-Amino-5-fluoro-2(1H)-pyrimidinone; 5-Fluoropyrimidine-2,4-diamine; Flucytosine (base); 5-Fluor-2,4-diaminopyrimidin; NSC 103805; 5-Fluoroisocytosine
EINECS	205-838-3

Quality Control

Our 2,4-Pyrimidinediamine, 5-Fluoro- is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed HPLC, NMR, and MS data upon request, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.