Description

5-Methyl-L-Tryptophan is a non-proteinogenic, methylated derivative of the essential amino acid L-tryptophan. This compound is of significant interest in biochemical research and pharmaceutical development due to its role as a potential modulator of tryptophan metabolism and serotonin synthesis pathways. It serves as a critical building block and research tool for scientists and manufacturers in the pharmaceutical, biotechnology, and advanced chemical synthesis sectors.

Application

• Pharmaceutical Intermediate: Used in the research and development of novel therapeutic agents, particularly those targeting neurological pathways and metabolic disorders.
• Biochemical Research: Acts as a key reagent and reference standard in studies of enzyme kinetics, amino acid transport, and metabolic pathway analysis.
• Peptide Synthesis: Serves as a specialized, protected amino acid building block for the synthesis of complex peptides and peptidomimetics with enhanced properties.
• Metabolic Studies: Employed in tracer studies and as an inhibitor to investigate the kynurenine and serotonin branches of tryptophan catabolism.
• Nutritional Science Research: Used in studies examining the effects of modified amino acids on growth, metabolism, and neurotransmitter balance.

Basic Information

Product Name	5-Methyl-L-Tryptophan
CAS No.	154-06-3
Molecular Formula	C12H14N2O2
Molecular Weight	218.25 g/mol
Synonyms	5-Methyl-L-tryptophan; (S)-2-Amino-3-(5-methyl-1H-indol-3-yl)propanoic acid; L-5-Methyltryptophan; 5-Methyl-L-Trp; 5-Methyl-L-α-amino-1H-indole-3-propanoic acid; 5-Methyl-L-indole-3-alanine; 5-Methyltryptophan, L-; 5-MTrp
EINECS	205-822-7

Quality Control

Our 5-Methyl-L-Tryptophan is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets high-purity research and development standards. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]	Contact for details
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.