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Allo-Dl-Threonine CAS NO 144-98-9


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CAS No.:144-98-9

Grade:Pharmacy Grade

Content:99.0%

Brand:Customizable

Packaging:Customizable

Description

Allo-Dl-Threonine is a non-proteinogenic stereoisomer of the essential amino acid L-threonine. This compound serves as a crucial chiral building block and intermediate in advanced organic synthesis and pharmaceutical research. It is primarily utilized by research institutions, pharmaceutical developers, and fine chemical manufacturers for applications in asymmetric synthesis, peptide chemistry, and the development of novel bioactive molecules.

Application

  • Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for antibiotics and metabolic drugs.
  • Biochemical Research: Used as a standard or reagent in enzymatic studies, metabolic pathway analysis, and as a component in custom cell culture media formulations.
  • Peptide Synthesis: Employed as a building block in solid-phase and solution-phase peptide synthesis to introduce structural diversity and study structure-activity relationships.
  • Asymmetric Catalysis: Acts as a precursor for chiral ligands, auxiliaries, or catalysts used in stereoselective chemical transformations.
  • Nutritional Science Studies: Utilized in comparative research to investigate the metabolism and biological effects of different threonine stereoisomers.
  • Reference Standard: Serves as an analytical standard in chromatography (HPLC, GC) for method development and quality control of related compounds.

Basic Information

Product Name Allo-Dl-Threonine
CAS No. 144-98-9
Molecular Formula C₄H₉NO₃
Molecular Weight 119.12 g/mol
Synonyms (2S,3R)-2-Amino-3-hydroxybutanoic acid; allo-Threonine; (±)-allo-Threonine; DL-allo-Threonine; three-2-Amino-3-hydroxybutyric acid; (R*,S*)-2-Amino-3-hydroxybutanoic acid; three-Threonine; α-Amino-β-hydroxybutyric acid (allo form)
EINECS 205-642-2

Quality Control

Our Allo-Dl-Threonine is manufactured under a strict quality management system. Each batch is subjected to comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing specific results for all critical parameters are provided and can be tailored to meet client-specific requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Optical Rotation Specific optical rotation data provided on COA
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm
Related Substances (HPLC) Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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