Description

B-(2-Thienyl)-D-Alanine is a non-proteinogenic amino acid derivative featuring a thiophene ring, which serves as a key chiral building block in organic synthesis. This compound is valued for its role in the development of novel pharmaceuticals and bioactive molecules, particularly in peptide-based drug discovery. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry and the synthesis of complex organic compounds.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the research and development of new therapeutic agents, including enzyme inhibitors and receptor modulators.
• Peptide Synthesis: Used to incorporate the thienylalanine moiety into custom peptides to study structure-activity relationships and enhance metabolic stability.
• Medicinal Chemistry Research: Serves as a building block in combinatorial chemistry and high-throughput screening libraries for drug discovery programs.
• Biochemical Studies: Employed as a substrate analog or inhibitor in enzymatic studies to investigate biological pathways and mechanisms.
• Agrochemical Development: Potential intermediate in the synthesis of novel, bioactive compounds for crop protection products.
• Academic Research: Used in university and institutional labs for synthetic organic chemistry projects and methodological development.

Basic Information

Product Name	B-(2-Thienyl)-D-Alanine
CAS No.	139-86-6
Molecular Formula	C7H9NO2S
Molecular Weight	171.22 g/mol
Synonyms	(R)-2-Amino-3-(thiophen-2-yl)propanoic acid; D-2-Thienylalanine; D-3-(2-Thienyl)alanine; (R)-3-(2-Thienyl)alanine; D-β-(2-Thienyl)alanine; β-(2-THIENYL)-D-ALANINE; (R)-2-Amino-3-(2-thienyl)propionic acid; 2-Thiophenealanine, D-
EINECS	205-379-7

Quality Control

Our B-(2-Thienyl)-D-Alanine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. We offer material suitable for research and development applications, with typical purity levels meeting or exceeding 98% (HPLC). A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and related substances is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.