Description

Betazole Hydrochloride is a histamine H2-receptor agonist, primarily used as a diagnostic agent in clinical pharmacology. This compound is critical for evaluating gastric acid secretory function and is a key tool in gastroenterological research. It is essential for pharmaceutical manufacturers, clinical diagnostic laboratories, and research institutions focused on gastrointestinal physiology and drug development.

Application

• Gastric Acid Secretion Testing: Used as a diagnostic agent (Histalog™) to stimulate gastric acid output for assessing stomach function.
• Pharmacological Research: Serves as a selective histamine H2-receptor agonist in studies of receptor function and signaling pathways.
• Drug Development: Employed as a reference standard and challenge agent in the development and testing of new H2-receptor antagonists and related therapeutics.
• Clinical Diagnostics: Integral to specialized diagnostic kits and protocols for evaluating conditions like Zollinger-Ellison syndrome or post-operative stomach analysis.
• Biochemical Studies: Used in vitro to study the effects of histamine receptor stimulation on various cell types and tissues.

Basic Information

Product Name	Betazole Hydrochloride
CAS No.	138-92-1
Molecular Formula	C5H9N3·HCl
Molecular Weight	147.60 g/mol
Synonyms	3-(2-Aminoethyl)pyrazole dihydrochloride; Histalog; Ametazole Hydrochloride; Betazole HCl; 1H-Pyrazole-3-ethanamine, hydrochloride (1:2); 3-(2-Aminoethyl)-1H-pyrazole dihydrochloride; Gastramine
EINECS	205-340-3

Quality Control

Our Betazole Hydrochloride is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets exacting standards for pharmaceutical and research use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.