Description

Edrophonium Chloride CAS NO 116-38-1 is a quaternary ammonium salt and a short-acting, reversible acetylcholinesterase inhibitor. This compound is a critical pharmaceutical intermediate and diagnostic agent, primarily valued for its rapid onset and short duration of action. It is essential for manufacturers and research institutions in the pharmaceutical and life sciences sectors, particularly for applications in neuromuscular function testing and as a reference standard.

Application

• Pharmaceutical Active Ingredient: Key intermediate in the synthesis of diagnostic and therapeutic agents targeting neuromuscular disorders.
• Diagnostic Agent: Used in the Tensilon test for the diagnosis of myasthenia gravis, helping to differentiate between myasthenic and cholinergic crises.
• Research Chemical: Vital tool in pharmacological and neurological research for studying cholinergic transmission, acetylcholinesterase inhibition, and neuromuscular junction physiology.
• Reference Standard: Serves as a high-purity analytical standard in quality control laboratories for HPLC, titration, and spectroscopic methods.
• Biochemical Reagent: Employed in enzymatic assays and in vitro studies to modulate acetylcholine levels.

Basic Information

Product Name	Edrophonium Chloride
CAS No.	116-38-1
Molecular Formula	C10H16ClNO
Molecular Weight	201.69 g/mol
Synonyms	Edrophonium Chloride; Ethyl(3-hydroxyphenyl)dimethylammonium Chloride; Tensilon Chloride; Antirex; Enlon; (3-Hydroxyphenyl)ethyldimethylammonium Chloride; Edrophone Chloride; Ro 1-9866
EINECS	204-135-1

Quality Control

Our Edrophonium Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent specifications for identity, purity, and potency, suitable for pharmaceutical and research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with relevant standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.