Description

Meglumine CAS NO 6284-40-8 is a versatile amino sugar derivative widely recognized as a key pharmaceutical excipient and diagnostic agent. Its primary value lies in its ability to form stable, water-soluble complexes with various ionic compounds, enhancing their bioavailability and safety profile. This makes it an essential component for manufacturers in the pharmaceutical, diagnostic imaging, and research sectors seeking reliable and high-purity chemical intermediates.

Application

• Pharmaceutical Formulations: Primarily used as an excipient and counterion in contrast media for diagnostic imaging, such as in meglumine diatrizoate and meglumine iotroxate.
• Diagnostic Agent: Serves as a crucial component in X-ray and CT scan contrast agents to improve visualization of internal organs and blood vessels.
• Chemical Synthesis: Acts as a chiral building block and complexing agent in the synthesis of various specialty chemicals and active pharmaceutical ingredients (APIs).
• Research & Development: Utilized in biochemical and pharmaceutical research for studying carbohydrate chemistry and developing new diagnostic compounds.
• Solubility Enhancer: Employed to increase the aqueous solubility of poorly soluble drugs and compounds in formulation development.

Basic Information

Product Name	Meglumine
CAS No.	6284-40-8
Molecular Formula	C7H17NO5
Molecular Weight	195.21 g/mol
Synonyms	1-Deoxy-1-(methylamino)-D-glucitol; N-Methylglucamine; Meglumin; Methylglucamine; D-Meglumine; N-Methyl-D-glucamine; Glucitol, 1-deoxy-1-(methylamino)-, D-; 1-Deoxy-1-methylaminosorbitol
EINECS	228-506-9

Quality Control

Our Meglumine is manufactured under strict quality management systems to ensure it meets the rigorous standards required for pharmaceutical and diagnostic applications. Each batch is tested against comprehensive specifications, including identity, purity, and impurity profiles, with methods aligned with major pharmacopoeias. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect product quality and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water (KF Titration)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	-15.5° to -17.5°
pH (5% solution)	10.0 - 11.5

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.