Description

Meglumine Diatrizoate is a high-purity, non-ionic iodinated contrast agent salt, essential for enhancing radiographic imaging clarity and safety. Its primary value lies in providing excellent water solubility and a favorable safety profile, making it a critical component in diagnostic medicine. This compound is specifically required by pharmaceutical manufacturers, diagnostic imaging centers, and research institutions developing advanced contrast media formulations.

Application

• X-ray Contrast Media: Key active pharmaceutical ingredient (API) in formulations for angiography, urography, and computed tomography (CT) scans.
• Diagnostic Pharmaceutical Manufacturing: Used in the synthesis of finished injectable solutions for vascular and cavity imaging.
• Medical Research: Serves as a standard reference material in pharmacokinetic studies and new contrast agent development.
• Veterinary Diagnostics: Employed in contrast imaging procedures for animals in veterinary clinics and research.
• Quality Control Laboratories: Acts as a system suitability standard and reference compound in HPLC and other analytical methods.

Basic Information

Product Name	Meglumine Diatrizoate
CAS No.	131-49-7
Molecular Formula	C18H26I3N3O9
Molecular Weight	809.13 g/mol
Synonyms	Diatrizoate Meglumine; Meglumine Amidotrizoate; N-Methylglucamine Diatrizoate; 3,5-Bis(acetylamino)-2,4,6-triiodobenzoic acid compound with 1-deoxy-1-(methylamino)-D-glucitol; MD-76; Gastrografin (component); Hypaque (component); Urografin (component); Meglumini Diatrizoas
EINECS	205-028-5

Quality Control

Our Meglumine Diatrizoate is manufactured and tested under a strict quality management system. It meets exacting standards for pharmaceutical-grade raw materials, with specifications aligned to major pharmacopoeias. A comprehensive Certificate of Analysis (COA) is provided with each batch, detailing results for identity, purity, assay, and impurity profiles to ensure regulatory compliance and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Free Iodide	≤ 0.05%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
pH (5% Solution)	6.5 - 8.0

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.