Description

Diatrizoate Sodium is a high-purity, iodinated organic compound widely recognized as a key contrast agent in diagnostic imaging. Its primary value lies in its ability to enhance X-ray visibility in various medical procedures, providing critical diagnostic clarity. This product is essential for manufacturers in the pharmaceutical and medical device industries, particularly for formulating injectable solutions used in angiography, urography, and other radiographic examinations.

Application

• Primary active pharmaceutical ingredient (API) in X-ray contrast media for diagnostic imaging.
• Formulation of injectable solutions for intravenous urography (IVU) and angiography.
• Used in computed tomography (CT) scans to visualize blood vessels and organs.
• Component in specialized contrast agents for hysterosalpingography and arthrography.
• Intermediate in the synthesis of other iodinated contrast agents and related pharmaceutical compounds.
• Research and development (R&D) applications in medical imaging and diagnostic sciences.

Basic Information

Product Name	Diatrizoate Sodium
CAS No.	737-31-5
Molecular Formula	C11H8I3N2NaO4
Molecular Weight	635.89 g/mol
Synonyms	Sodium Diatrizoate; Amidotrizoate Sodium; 3,5-Bis(acetylamino)-2,4,6-triiodobenzoic Acid Sodium Salt; Hypaque Sodium; Gastrografin (component); Urografin (component); Renografin (component); MD-76
EINECS	212-004-6

Quality Control

Our Diatrizoate Sodium is manufactured under strict quality management systems, targeting compliance with pharmaceutical-grade standards such as USP/EP monographs. Each batch undergoes rigorous analytical testing, including assay, impurity profiling, and residual solvent analysis. A comprehensive Certificate of Analysis (COA) is provided with every shipment to ensure traceability and confirm specification adherence.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); protect from humidity and absorb moisture promptly upon opening.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water (KF Titration)	≤ 5.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Free Iodide	≤ 0.05%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
pH (5% Solution)	6.5 - 8.0
Bacterial Endotoxins	< 1.0 EU/mg (where applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.