Description

Indocyanine Green is a water-soluble, tricarbocyanine dye with near-infrared fluorescence properties. This compound is critically important as a diagnostic and imaging agent in modern medical and biomedical research. It is primarily needed by pharmaceutical manufacturers, clinical research organizations, and diagnostic developers for applications in angiography, sentinel lymph node mapping, and ophthalmic imaging.

Application

• Medical Diagnostics: Used as a contrast agent for fluorescence angiography in ophthalmology to visualize retinal and choroidal circulation.
• Surgical Guidance: Employed in sentinel lymph node biopsy procedures for cancer staging, particularly in breast cancer and melanoma surgery.
• Hepatic Function Assessment: Utilized in liver function tests to measure cardiac output, hepatic blood flow, and blood volume.
• Biomedical Research: Serves as a near-infrared (NIR) fluorescent probe for in vivo and in vitro imaging, including tumor targeting and vascular permeability studies.
• Photodynamic Therapy (PDT): Investigated as a potential photosensitizer in experimental cancer treatment protocols.
• Microscopy & Staining: Applied in specialized histological and cellular imaging techniques that utilize NIR fluorescence.

Basic Information

Product Name	Indocyanine Green
CAS No.	3599-32-4
Molecular Formula	C43H47N2NaO6S2
Molecular Weight	774.96 g/mol
Synonyms	ICG; Cardio-Green; Fox Green; Infracyanine Green; Ujoviridin; 2-[7-[1,3-Dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e]indol-2-ylidene]-1,3,5-heptatrienyl]-1,1-dimethyl-3-(4-sulfobutyl)-1H-benz[e]indolium hydroxide, inner salt, sodium salt
EINECS	Contact for details

Quality Control

Our Indocyanine Green is manufactured under strict quality systems suitable for diagnostic and research applications. Each batch is tested to ensure high purity and performance consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and related substance profiles is provided with every shipment. We support compliance with relevant pharmacopeial standards (e.g., USP, EP) for specific grades upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label. This material is strictly light-sensitive (protect from all light exposure) and easily oxidized (store under inert atmosphere). Keep the container tightly sealed in a dry, cool, and well-ventilated place.

Specification

Item	Specification
Appearance	Dark green to bluish-black powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥95.0% (on anhydrous basis)
Water Content	≤5.0% (Karl Fischer)
Residue on Ignition	≤1.0%
Heavy Metals	≤20 ppm
Absorbance (λ max)	780-810 nm (in aqueous solution)
Fluorescence	Emission ~820 nm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.