Description

10-Formylfolic Acid is a key folate derivative and biochemical intermediate of significant interest in pharmaceutical research and development. This compound serves as a crucial precursor in the synthesis of more complex folate analogs and plays a vital role in one-carbon metabolism studies. It is primarily utilized by research institutions, pharmaceutical manufacturers, and fine chemical producers engaged in developing novel therapeutics, diagnostic agents, and high-purity biochemical standards.

Application

• Pharmaceutical Intermediate: Critical precursor in the synthesis of advanced folate-based drugs and targeted chemotherapeutic agents.
• Biochemical Research: Used as a standard and reagent in studies of folate metabolism, enzyme kinetics, and one-carbon transfer pathways.
• Nutraceutical Development: Serves as a starting material for the development of specialized folate supplements and fortified food ingredients.
• Diagnostic Reagent Manufacturing: Employed in the production of components for clinical diagnostic kits and assays measuring folate levels.
• Reference Standard: Provides a high-purity standard for quality control in pharmaceutical and nutritional product analysis.

Basic Information

Item	Details
Product Name	10-Formylfolic Acid
CAS No.	134-05-4
Molecular Formula	C₂₀H₂₁N₇O₇
Molecular Weight	471.43 g/mol
Synonyms	10-Formylfolic Acid; 10-Formylfolate; 10-CHO-FA; 10-Formyltetrahydrofolic Acid; N10-Formylfolic Acid; N10-Formyltetrahydrofolate; 10-Formyl-5,6,7,8-tetrahydropteroylglutamic Acid; Leucovorin Impurity A
EINECS	205-126-1

Quality Control

Our 10-Formylfolic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets exacting standards for research and pharmaceutical use. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.