Description

D-Erythro-Sphingosine is a fundamental bioactive sphingolipid backbone, essential for cellular signaling and membrane structure. This high-purity compound is critical for researchers and manufacturers developing advanced therapeutics and studying complex metabolic pathways. It is primarily utilized in pharmaceutical R&D, life science research, and the synthesis of more complex sphingolipids for biochemical applications.

Application

• Pharmaceutical Research & Development: A key intermediate and reference standard in the development of novel cancer therapies, immunomodulators, and drugs targeting sphingolipid metabolism.
• Biochemical Synthesis: Serves as the foundational building block for the synthesis of ceramides, sphingomyelins, glycosphingolipids, and other complex signaling molecules.
• Cell Biology & Signal Transduction Studies: Used to investigate apoptosis, cell proliferation, differentiation, and response to stress by modulating intracellular sphingolipid levels.
• Cosmeceutical Ingredient Development: Explored for its role in skin barrier function and as a precursor for ceramides used in high-end skincare formulations.
• Academic & Industrial Research: An essential tool for studying lipid rafts, membrane biophysics, and the role of sphingolipids in neurological and metabolic diseases.
• Diagnostic Reagent Manufacturing: Used in the production of assay kits and reagents for detecting and quantifying sphingolipid-related enzymes and metabolites.

Basic Information

Product Name	D-Erythro-Sphingosine
CAS No.	123-78-4
Molecular Formula	C18H37NO2
Molecular Weight	299.49 g/mol
Synonyms	(2S,3R)-2-Amino-3-hydroxyoctadec-4-ene; Erythro-sphingosine; Sphing-4-enine; D-erythro-2-Amino-4-octadecene-1,3-diol; trans-4-Sphingenine; (E)-Sphing-4-enine; Sphingosine (D-erythro- form); 4-Sphingenine
EINECS	204-651-3

Quality Control

Our D-Erythro-Sphingosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements of research and pharmaceutical applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and moisture absorption. Allow the sealed container to reach room temperature before opening to minimize condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Specific Rotation	+4.0° to +6.0° (c=1 in CHCl3)
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.