Description

p-Hydroxyphenylpyruvic Acid Monosodium Salt is a key biochemical intermediate, the monosodium salt form of the tyrosine metabolite 4-hydroxyphenylpyruvic acid. This compound is of significant importance in pharmaceutical research and synthesis, particularly as a precursor in the production of L-DOPA and other catecholamines. It is primarily needed by manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for use in active pharmaceutical ingredient (API) synthesis, metabolic pathway studies, and as a reference standard.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of L-DOPA (Levodopa), a primary medication for Parkinson's disease.
• Biochemical Research: Used as a substrate or standard in enzymatic studies, particularly those involving tyrosine metabolism and phenylalanine/tyrosine aminotransferases.
• Fine Chemical Synthesis: Serves as a building block for the production of various catechol derivatives and specialty organic compounds.
• Metabolite Reference Standard: Employed in analytical laboratories for HPLC, LC-MS, or GC-MS method development and validation in clinical and diagnostic testing.
• Nutraceutical Development: Investigated for use in the research and development of compounds targeting metabolic disorders.

Basic Information

Product Name	p-Hydroxyphenylpyruvic Acid Monosodium Salt
CAS No.	114-75-0
Molecular Formula	C9H7NaO4 • xH2O
Molecular Weight	202.14 (Anhydrous)
Synonyms	4-Hydroxyphenylpyruvic Acid Monosodium Salt; Sodium 4-Hydroxyphenylpyruvate; HPPA Sodium Salt; (4-Hydroxyphenyl)pyruvic Acid Sodium Salt; p-Hydroxyphenylpyruvate Sodium; Monosodium 4-Hydroxyphenylpyruvate; 4-HPPA-Na; Tyrosine Metabolite Sodium Salt
EINECS	204-052-6

Quality Control

Our p-Hydroxyphenylpyruvic Acid Monosodium Salt is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and residual solvents. Our quality commitment supports applications requiring high-purity biochemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed after opening to minimize exposure to atmospheric moisture and light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines
pH (5% solution)	6.0 - 8.0

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.