Description

Malantide is a potent and selective peptide inhibitor of protein phosphatase 2A (PP2A), a key regulatory enzyme in cellular signaling pathways. Its high specificity makes it an invaluable research tool for studying signal transduction mechanisms related to cell growth, metabolism, and apoptosis. This compound is primarily utilized by researchers and developers in the pharmaceutical, biotechnology, and life sciences sectors for biochemical assay development and target validation.

Application

• Biochemical Research: Used as a specific inhibitor to study the role of PP2A in various cellular processes and signaling cascades.
• Drug Discovery: Employed in high-throughput screening assays to identify novel therapeutics targeting phosphatase-related diseases.
• Cell Biology Studies: Applied to investigate the effects of PP2A inhibition on cell cycle regulation, differentiation, and programmed cell death.
• Neuroscience Research: Utilized to explore PP2A's function in neuronal signaling, synaptic plasticity, and neurodegenerative conditions.
• Enzyme Kinetics: Serves as a reference compound for characterizing PP2A activity and inhibitor potency in vitro.
• Academic & Institutional R&D: A key reagent for universities and research institutes conducting fundamental research in molecular biology and biochemistry.

Basic Information

Product Name	Malantide
CAS No.	86555-35-3
Molecular Formula	C58H95N17O13
Molecular Weight	1206.5 g/mol
Synonyms	Malantide; PP2A Inhibitor Peptide; H-Arg-Pro-Ile-Pro-Ala-Leu-Leu-Arg-Arg-Leu-Ile-Ser-Ser-Leu-Phe-NH2; H-Arg-Pro-Ile-Pro-Ala-Leu-Leu-Arg-Arg-Leu-Ile-Ser-Ser-Leu-Phe-amide; Protein Phosphatase 2A Inhibitor (661-676) amide, human; Malantide trifluoroacetate salt
EINECS	Contact for details

Quality Control

Our Malantide is produced under stringent quality management systems to ensure batch-to-batch consistency and reliability for critical research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity verification and mass spectrometry for identity confirmation. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Assay (Peptide Content)	≥ 80%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.