Description

Seglitide CAS NO 81377-02-8 is a synthetic cyclic hexapeptide and a potent somatostatin analog. This compound is of significant interest in pharmaceutical research and development due to its high binding affinity for somatostatin receptors. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics for endocrine disorders and oncology.

Application

• Pharmaceutical Research & Development: A key reference standard and active pharmaceutical ingredient (API) intermediate in the development of somatostatin-based therapies.
• Endocrinology Studies: Used in preclinical research to investigate the regulation of growth hormone, insulin, and glucagon secretion.
• Oncology Research: Employed in studies targeting somatostatin receptor-positive tumors, such as neuroendocrine tumors, for potential diagnostic and therapeutic applications.
• Biochemical Tool: Serves as a critical ligand in receptor binding assays and pharmacological characterization of somatostatin receptor subtypes.
• Peptide Chemistry Reference: Used as a model compound in methodological development for peptide synthesis, purification, and analysis.

Basic Information

Product Name	Seglitide
CAS No.	81377-02-8
Molecular Formula	C37H51N9O9S2
Molecular Weight	829.99 g/mol
Synonyms	MK-678; L-363,586; Cyclo(N-Me-Ala-Tyr-D-Trp-Lys-Val-Phe); Somatostatin analog MK 678; [N-Me-Ala1,Tyr2,D-Trp3,Lys4,Val5,Phe6]-Somatostatin-14(1-6)-lactam
EINECS	Contact for details

Quality Control

Our Seglitide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets rigorous specifications for research use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.