Description

Septide CAS NO 79775-19-2 is a synthetic peptide compound known for its role as a selective antagonist of the neuropeptide S (NPS) receptor. This specificity makes it a valuable research tool for investigating the NPS system, which is implicated in various physiological processes including anxiety, arousal, and addiction. It is primarily utilized by pharmaceutical researchers, academic institutions, and biotechnology companies engaged in neuroscience and central nervous system (CNS) drug discovery.

Application

• Neuroscience Research: A key pharmacological tool for studying the function and signaling pathways of the Neuropeptide S (NPS) receptor in the brain.
• Behavioral Pharmacology: Used in preclinical models to investigate the role of the NPS system in anxiety, stress response, wakefulness, and locomotor activity.
• Drug Discovery & Development: Serves as a reference compound for screening and validating new NPS receptor antagonists or modulators for potential therapeutic applications.
• Academic & Institutional Studies: Employed in university and research institute labs for fundamental research into neuropeptide biology and receptor-ligand interactions.
• Biochemical Assay Development: Used as a standard in developing and optimizing in vitro binding assays (e.g., radioligand binding) and functional assays for the NPS receptor.

Basic Information

Product Name	Septide
CAS No.	79775-19-2
Molecular Formula	C58H84N16O13S
Molecular Weight	1221.44 g/mol
Synonyms	NPS Receptor Antagonist; [D-Cys(tBu)5]NPS; Neuropeptide S Antagonist; H-Asp-Arg-Val-Pro-D-Cys(tBu)-Gly-Leu-Val-NH2; Cyclo(5-10)[Asp1, Arg2, Val3, Pro4, D-Cys(tBu)5, Gly6, Leu7, Val8]NPS(1-10) amide; Septide Acetate; GPR154 Ligand
EINECS	Contact for details

Quality Control

Our Septide is manufactured under strict quality management systems to ensure batch-to-batch consistency and reliability for research purposes. Each lot undergoes comprehensive analytical testing, including HPLC for purity and mass spectrometry (MS) for identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the specific results for your critical review.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC-MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80%
Single Impurity (HPLC)	≤ 2.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.