Description

D-Valine CAS NO 640-68-6 is the D-enantiomer of the essential branched-chain amino acid valine, distinguished by its specific stereochemistry. This non-proteinogenic isomer is a critical chiral building block and resolving agent in advanced organic synthesis and pharmaceutical research. It is primarily utilized by research institutions, pharmaceutical developers, and fine chemical manufacturers engaged in peptide synthesis, asymmetric catalysis, and the production of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of enantiomerically pure drugs, antibiotics, and complex bioactive molecules.
• Peptide Synthesis & Research: Used to incorporate D-amino acids into synthetic peptides and peptidomimetics to study structure-activity relationships and enhance metabolic stability.
• Microbiological & Cell Culture Media: Employed in selective media formulations to inhibit the growth of certain bacterial strains or specific cell types in biotechnological applications.
• Chiral Resolution Agent: Serves as a resolving agent for the separation of racemic mixtures of acids or other compounds via diastereomeric salt formation.
• Biochemical Research: A fundamental tool in enzymology and metabolic pathway studies to investigate enzyme specificity and amino acid metabolism.
• Asymmetric Synthesis Catalyst: Used in the preparation of chiral ligands and auxiliaries for catalytic asymmetric transformations.

Basic Information

Product Name	D-Valine
CAS No.	640-68-6
Molecular Formula	C5H11NO2
Molecular Weight	117.15 g/mol
Synonyms	(R)-Valine; (R)-2-Amino-3-methylbutanoic acid; D-2-Amino-3-methylbutyric acid; (R)-2-Azaniumyl-3-methylbutanoate; H-D-Val-OH; D-α-Aminoisovaleric Acid
EINECS	211-382-0

Quality Control

Our D-Valine is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity verification, to ensure it meets stringent specifications for research and pharmaceutical applications. Certificates of Analysis (COA) detailing identity, purity (by HPLC), optical rotation, and residual solvent levels are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.5%
Optical Rotation [α]D20	-26° to -30° (c=1 in H2O)
Chiral Purity (HPLC)	≥ 99.0% D-isomer
Loss on Drying	≤ 0.5%
Residue on Ignition (Sulfated Ash)	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.