Description

D-Threonine is a non-essential amino acid and the D-isomer of threonine, distinguished by its specific stereochemistry. This enantiomerically pure compound is a critical building block in the synthesis of chiral pharmaceuticals, peptides, and fine chemicals, where precise molecular configuration is paramount for biological activity. It serves as a key intermediate for research and production in the pharmaceutical, biotechnology, and nutraceutical industries, particularly in the development of antibiotics, enzyme inhibitors, and specialized nutritional formulations.

Application

• Pharmaceutical Intermediate: A crucial chiral building block for the synthesis of antibiotics, antiviral agents, and other active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to create peptides with specific, defined stereochemistry for research and therapeutic applications.
• Biochemical Research: Employed as a standard or reagent in enzymatic studies, metabolic pathway analysis, and microbiological culture media preparation.
• Nutraceutical Formulations: Incorporated into specialized dietary supplements and infusion solutions where the specific D-isomer is required.
• Asymmetric Catalysis: Serves as a chiral ligand or precursor in asymmetric synthesis for producing enantiomerically enriched compounds.
• Food & Flavor Industry: Used in the research and development of flavor enhancers and certain food additives.

Basic Information

Product Name	D-Threonine
CAS No.	632-20-2
Molecular Formula	C4H9NO3
Molecular Weight	119.12 g/mol
Synonyms	(2R,3S)-2-Amino-3-hydroxybutanoic acid; D-(-)-Threonine; (R*,S*)-Threonine; (2R,3S)-Threonine; D-allo-Threonine; (R)-Threonine; D-Thr; H-D-Thr-OH
EINECS	211-171-9

Quality Control

Our D-Threonine is manufactured under strict quality management systems. We offer material compliant with various pharmacopeial standards, including USP and EP grades, upon request. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing assay, chiral purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent absorption of moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	≥98.5%
Optical Rotation [α]20/D	-28.0° to -30.0° (c=1 in H2O)
Chiral Purity (HPLC)	≥99.0% (D-isomer)
Loss on Drying	≤0.5%
Residue on Ignition (Sulfated Ash)	≤0.1%
Heavy Metals (as Pb)	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.