Description

L-Hydroxyproline is a vital non-essential amino acid derivative, a key structural component of collagen and other connective tissue proteins. Its unique cyclic structure provides stability and is essential for maintaining the integrity of skin, bones, tendons, and cartilage. This high-purity ingredient is primarily sought by manufacturers in the pharmaceutical, nutraceutical, and cosmetic industries for applications ranging from joint health supplements to advanced wound healing formulations and anti-aging skincare products.

Application

• Pharmaceutical Intermediates: Critical raw material for synthesizing collagen-based drugs, wound healing agents, and treatments for connective tissue disorders.
• Dietary Supplements & Nutraceuticals: Core ingredient in formulations targeting joint health, skin elasticity, bone strength, and overall connective tissue support.
• Cosmetics & Personal Care: Used in anti-aging serums, creams, and lotions for its role in promoting collagen synthesis and improving skin hydration and firmness.
• Biochemical Research & Cell Culture: Essential component in media for studying collagen metabolism, fibroblast growth, and tissue engineering applications.
• Veterinary Medicine: Incorporated into supplements and therapeutic feeds for animal joint and mobility support.
• Food Science: Studied for potential use in functional foods and as a marker for collagen content in food products.

Basic Information

Product Name	L-Hydroxyproline
CAS No.	51-35-4
Molecular Formula	C5H9NO3
Molecular Weight	131.13 g/mol
Synonyms	(2S,4R)-4-Hydroxypyrrolidine-2-carboxylic acid; L-4-Hydroxyproline; (4R)-L-Hydroxyproline; Hyp; Oxoproline; L-4-Hydroxy-2-pyrrolidinecarboxylic acid; NSC 23188; L(-)-Hydroxyproline
EINECS	200-068-1

Quality Control

Our L-Hydroxyproline is manufactured under strict quality management systems. We offer grades suitable for pharmaceutical, nutraceutical, and research applications, with specifications that can meet or exceed relevant standards such as USP, EP, and FCC. Every batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles to ensure consistency and regulatory compliance for your critical formulations.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.5%
Specific Rotation	-74° to -78° (c=1 in H2O)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.