Description

Kisspeptin 10 (Human) CAS NO 374675-21-5 is a bioactive decapeptide fragment of the kisspeptin protein, playing a critical role in the hypothalamic-pituitary-gonadal axis. This compound is essential for initiating the secretion of gonadotropin-releasing hormone (GnRH), making it a vital research tool for studying reproductive biology and neuroendocrinology. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on developing therapeutics for fertility disorders, puberty-related conditions, and hormone-dependent cancers.

Application

• Neuroendocrine Research: Fundamental studies on the regulation of GnRH pulse generation and the central control of reproduction.
• Fertility & Reproductive Health R&D: Investigation of kisspeptin signaling pathways for potential therapeutic interventions in infertility, polycystic ovary syndrome (PCOS), and hypogonadism.
• Preclinical Drug Development: Serving as a reference standard and active pharmaceutical ingredient (API) in the development of kisspeptin-based diagnostics and treatments.
• Cancer Research: Exploration of its role as a metastasis suppressor in studies related to breast cancer, prostate cancer, and other malignancies.
• Veterinary Science: Research into reproductive management and breeding programs for livestock and companion animals.
• Biochemical Assay Development: Used as a critical component in ELISA kits, receptor binding assays, and other in vitro test systems.

Basic Information

Product Name	Kisspeptin 10 (Human)
CAS No.	374675-21-5
Molecular Formula	C₆₀H₈₆N₁₈O₁₄
Molecular Weight	1267.5 g/mol
Synonyms	Kisspeptin-10; Kp-10; Metastin (45-54); hKp-10; Kiss-1 (112-121); Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH₂; KISS1 (112-121); Human Metastin 45-54 amide
EINECS	Contact for details

Quality Control

Our Kisspeptin 10 (Human) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and mass spectrometry (MS) for identity confirmation. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing purity, peptide content, and solvent residues. Our production adheres to cGMP guidelines for research-grade peptides.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry environment before opening to prevent condensation and hydrolysis. Aliquot into working quantities to minimize freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Amino Acid Analysis	Within ± 10% of theoretical
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.