Description

D-Alanine CAS NO 338-69-2 is the D-isomer of the non-essential amino acid alanine, a key chiral building block in organic synthesis and pharmaceutical manufacturing. Its primary value lies in its role as a precursor for the synthesis of various peptides, antibiotics, and other bioactive compounds where stereochemical purity is critical. This high-purity enantiomer is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries developing novel therapeutics and advanced materials.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of antibiotics (e.g., β-lactams), antiviral drugs, and other active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used as a protected or unprotected amino acid building block in solid-phase and solution-phase peptide synthesis for research and therapeutic peptides.
• Biochemical Research: Essential component in cell culture media, enzyme studies, and metabolic pathway research as a specific substrate or inhibitor.
• Food & Nutritional Science: Employed in the study of flavor enhancers (umami taste) and the development of specialized nutritional supplements.
• Cosmetic & Personal Care: Incorporated into the formulation of moisturizing and skin-conditioning agents due to its role in natural moisturizing factors (NMF).
• Agrochemical Development: Serves as a chiral synthon in the production of certain herbicides and plant growth regulators.

Basic Information

Product Name	D-Alanine
CAS No.	338-69-2
Molecular Formula	C3H7NO2
Molecular Weight	89.09 g/mol
Synonyms	(R)-Alanine; D-2-Aminopropionic Acid; (R)-2-Aminopropanoic Acid; D-α-Alanine; (R)-(−)-Alanine; D-Ala; H-D-Ala-OH; NSC 7604
EINECS	206-418-1

Quality Control

Our D-Alanine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity assay and impurity profiling, to ensure it meets the high standards required for pharmaceutical and research applications. Certificates of Analysis (COA) detailing specific results for purity, optical rotation, and residual solvents are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed in a dry environment to prevent absorption of moisture, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.5%
Optical Rotation [α]D20	-14.0° to -15.0° (c=1 in 1N HCl)
Chiral Purity (HPLC)	≥ 99.0% D-isomer
Loss on Drying	≤ 0.5%
Residue on Ignition (Sulfated Ash)	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.