Description

H-Leu-Leu-Oh is a high-purity dipeptide derivative, specifically the methyl ester of the leucine-leucine dipeptide. This compound serves as a crucial building block and intermediate in advanced organic synthesis and peptide research. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers for developing novel therapeutic agents and biochemical tools.

Application

• Pharmaceutical Intermediate: Key starting material for the synthesis of more complex peptide-based drugs and protease inhibitors.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving peptidases and proteases.
• Peptide Synthesis: An essential protected dipeptide unit in solid-phase and solution-phase peptide chemistry for constructing longer peptide chains.
• Proteomics: Employed in the development of chemical probes and activity-based protein profiling (ABPP) reagents.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	H-Leu-Leu-Oh
CAS No.	3303-31-9
Molecular Formula	C12H24N2O3
Molecular Weight	244.33 g/mol
Synonyms	L-Leucyl-L-leucine methyl ester; Leu-Leu-OMe; Methyl L-leucyl-L-leucinate; H-Leu-Leu-OMe; L-Leucine, L-leucyl-, methyl ester; NSC 334358; Methyl N-[(2S)-1-hydroxy-4-methyl-1-oxopentan-2-yl]-L-leucinate; (S)-Methyl 2-((S)-2-amino-4-methylpentanamido)-4-methylpentanoate
EINECS	Contact for details

Quality Control

Our H-Leu-Leu-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification, to ensure it meets exacting standards for research and synthesis. Certificates of Analysis (COA) with full traceability are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.