Description

D-Serine is the D-enantiomer of the non-essential amino acid serine, a key chiral building block with significant biological activity. This high-purity compound is essential for advanced research and manufacturing processes where stereochemical specificity is critical. It is primarily utilized by the pharmaceutical, biotechnology, and fine chemical synthesis industries for applications ranging from neurological research to the production of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediates: A crucial chiral precursor in the synthesis of complex APIs, antibiotics, and other therapeutic agents.
• Neurological Research: Used as a selective agonist of the glycine site on the NMDA (N-methyl-D-aspartate) receptor for studying synaptic plasticity and CNS disorders.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies and as a component in cell culture media and diagnostic reagents.
• Peptide Synthesis: An important D-form amino acid for constructing peptides with enhanced stability and specific biological properties.
• Food & Nutrition: Potential application in the development of specialized nutritional supplements and flavoring agents.
• Cosmetic Ingredients: Used in the formulation of high-end skincare products for its potential moisturizing and skin-conditioning properties.

Basic Information

Product Name	D-Serine
CAS No.	312-84-5
Molecular Formula	C3H7NO3
Molecular Weight	105.09 g/mol
Synonyms	(R)-2-Amino-3-hydroxypropanoic acid; (R)-Serine; D-(-)-Serine; (R)-(-)-Serine; (2R)-2-Amino-3-hydroxypropanoic acid; D-α-Amino-β-hydroxypropionic acid; Right-handed serine
EINECS	206-229-4

Quality Control

Our D-Serine is manufactured under a strict quality management system to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical documentation, including a detailed Certificate of Analysis (COA) for each lot, verifying parameters such as assay, enantiomeric excess, and impurity profiles. The product meets stringent specifications suitable for research and GMP-grade applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent absorption of moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.5%
Enantiomeric Purity	≥ 99.0% (D-Isomer)
Specific Rotation [α]20/D	-14.5° to -16.0° (c=1 in 1N HCl)
Loss on Drying	≤ 0.5%
Residue on Ignition (Sulfated Ash)	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.