Description

n-Acetyl-L-Phenylalanine is a chemically modified derivative of the essential amino acid L-Phenylalanine, where an acetyl group protects the amino functionality. This modification is crucial for its role as a key chiral building block and intermediate in the synthesis of more complex bioactive molecules. It is primarily utilized by the pharmaceutical, biotechnology, and fine chemical industries for research and production purposes.

Application

• Pharmaceutical Intermediate: A critical chiral precursor in the synthesis of peptide-based drugs, enzyme inhibitors, and other active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a substrate or standard in enzymatic studies, metabolic pathway analysis, and proteomics research.
• Peptide Synthesis: Serves as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis (SPPS) to prevent unwanted side reactions.
• Food & Nutrition Science: Investigated for potential applications in flavor enhancement and as a metabolic precursor in specialized nutritional formulations.
• Cosmetic Ingredient: Employed in the development of advanced skincare products for its potential role in peptide-based anti-aging formulations.

Basic Information

Product Name	n-Acetyl-L-Phenylalanine
CAS No.	2018-61-3
Molecular Formula	C11H13NO3
Molecular Weight	207.23 g/mol
Synonyms	N-Acetyl-L-phenylalanine; N-Acetylphenylalanine; Ac-Phe-OH; (2S)-2-Acetamido-3-phenylpropanoic acid; L-α-Acetamidohydrocinnamic acid; N-Acetyl-L-α-phenylalanine; NSC 3340; N-Acetyl-(S)-phenylalanine
EINECS	217-958-2

Quality Control

Our n-Acetyl-L-Phenylalanine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm enantiomeric excess, and identity confirmation via IR and NMR. We provide full traceability and Certificates of Analysis (COA) are available for all shipments to ensure compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.5%
Optical Rotation [α]20/D	-30.0° to -35.0° (c=1 in H2O)
Chiral Purity (HPLC)	≥ 99.0% (L-Isomer)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.