Description

(+/-)-6-Methylnicotine CAS NO 101540-79-8 is a high-purity, synthetic nicotine analog of significant interest in advanced chemical research and development. This compound serves as a critical intermediate and reference standard for investigating nicotinic acetylcholine receptor (nAChR) pharmacology and developing novel chemical entities. It is primarily utilized by pharmaceutical R&D laboratories, agrochemical innovators, and specialty chemical manufacturers requiring precise molecular tools for synthesis and biological studies.

Application

• Pharmaceutical Research Intermediate: A key building block in the synthesis of novel drug candidates targeting neurological pathways.
• Neuroscience & Receptor Studies: Used as a reference standard and ligand in pharmacological research on nicotinic acetylcholine receptors (nAChRs).
• Agrochemical Development: Serves as a precursor or model compound in the design of new crop protection agents with selective activity.
• Chemical Synthesis: Employed in organic synthesis for the preparation of more complex nicotine derivatives and analogs.
• Analytical Reference Standard: Provides a high-purity benchmark for quality control and method development in analytical laboratories (HPLC, GC, LC-MS).
• Biochemical Tool Compound: Utilized in *in vitro* assays to study binding affinity, metabolic pathways, and structure-activity relationships (SAR).

Basic Information

Product Name	(+/-)-6-Methylnicotine
CAS No.	101540-79-8
Molecular Formula	C11H16N2
Molecular Weight	176.26 g/mol
Synonyms	6-Methylnicotine (racemic); DL-6-Methylnicotine; (±)-6-Methylnicotine; 1-Methyl-2-(6-methyl-3-pyridyl)pyrrolidine; 3-[(2S)-1-Methylpyrrolidin-2-yl]-6-methylpyridine (racemate); Nicotine, 6-methyl- (racemic); Pyridine, 3-(1-methyl-2-pyrrolidinyl)-6-methyl-, (+/-)-
EINECS	Contact for details

Quality Control

Our (+/-)-6-Methylnicotine is manufactured under controlled conditions to ensure batch-to-batch consistency and high chemical purity. Quality is verified through a comprehensive suite of analytical techniques including HPLC, GC, and NMR spectroscopy. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This material is light-sensitive and easily oxidized; prolonged exposure to air or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.