Description

[(1S,3S)-3-[[4-Methoxy-3-(3-methoxypropoxy)phenyl]methyl]-4-methyl-1-[(2S, 4R)-tetrahydro-4-(1-methylethyl)-5-oxo-2-furanyl]pentyl]carbamic Acid 1,1-tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate with a complex, stereochemically defined structure. This compound is critical for ensuring the quality and efficacy of final active pharmaceutical ingredients (APIs) in sophisticated drug development pipelines. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the synthesis of novel therapeutic agents, particularly within oncology and other specialized therapeutic areas.

Application

This specialized intermediate serves as a key building block in advanced organic synthesis. Its primary applications include:

• Pharmaceutical Intermediate: Critical precursor in the multi-step synthesis of complex, target-specific Active Pharmaceutical Ingredients (APIs).
• Drug Discovery & Development: Used in medicinal chemistry for the research and development of new chemical entities, especially in oncology and antiviral research.
• Process Chemistry & Scale-Up: Employed in optimizing synthetic routes from laboratory scale to commercial manufacturing under cGMP conditions.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation during API production.
• Custom Synthesis: A starting material for the contract manufacturing of bespoke molecules for clinical trials.

Basic Information

Product Name	[(1S,3S)-3-[[4-Methoxy-3-(3-methoxypropoxy)phenyl]methyl]-4-methyl-1-[(2S, 4R)-tetrahydro-4-(1-methylethyl)-5-oxo-2-furanyl]pentyl]carbamic Acid 1,1-tert-Butyl Ester
CAS No.	900811-52-1
Molecular Formula	C31H49NO7
Molecular Weight	547.73 g/mol
Synonyms	(1S,3S)-3-[[4-Methoxy-3-(3-methoxypropoxy)phenyl]methyl]-4-methyl-1-[(2S,4R)-tetrahydro-4-(1-methylethyl)-5-oxo-2-furanyl]pentyl]carbamic acid 1,1-dimethylethyl ester; tert-Butyl N-[(1S,3S)-3-[[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl]-4-methyl-1-[(2S,4R)-4-propan-2-yl-5-oxooxolan-2-yl]pentyl]carbamate; A key Telaprevir intermediate; Telaprevir impurity standard; VX-950 intermediate; Advanced protease inhibitor intermediate.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality management systems. Every batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our quality commitment supports development and manufacturing processes requiring material traceability and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in a desiccated environment after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.