Description

n-Boc-Pyrroline is a versatile and high-purity protected heterocyclic amine, serving as a critical building block in advanced organic synthesis. Its primary value lies in the Boc (tert-butoxycarbonyl) protecting group, which safeguards the pyrroline nitrogen during multi-step reactions, enabling the precise construction of complex molecules. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing novel active compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of drug candidates, particularly those containing pyrrolidine or proline motifs, such as protease inhibitors and neurological agents.
• Peptide Mimetics & PROTACs: Used to introduce constrained ring systems and amine functionalities into peptide backbones and heterobifunctional degraders.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and insecticides with enhanced biological activity.
• Material Science: Monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and labeled compounds for biochemical research.
• Asymmetric Catalysis: Chiral precursor for synthesizing ligands used in asymmetric hydrogenation and other catalytic processes.

Basic Information

Product Name	n-Boc-Pyrroline
CAS No.	73286-70-1
Molecular Formula	C9H15NO2
Molecular Weight	169.22 g/mol
Synonyms	1-Boc-2,5-Dihydro-1H-pyrrole; 1-(tert-Butoxycarbonyl)-2,5-dihydro-1H-pyrrole; tert-Butyl 2,5-dihydro-1H-pyrrole-1-carboxylate; N-Boc-2,5-Dihydropyrrole; N-Boc-3,4-dihydro-2H-pyrrole; N-(tert-Butoxycarbonyl)-2,5-dihydro-1H-pyrrole; 1-Boc-3-pyrroline; 1-N-Boc-3-pyrroline
EINECS	Contact for details

Quality Control

Our n-Boc-Pyrroline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support compliance with cGMP, ISO, and other relevant regulatory frameworks for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.