Description

2-(2,4-Dichloro-5-Fluorophenyl)Piperazine CAS NO 914348-92-8 is a high-purity, functionalized piperazine derivative serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs). This compound is essential for research and manufacturing organizations in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new therapeutic agents and high-performance materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) agents, antimicrobials, and oncology therapeutics.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, leveraging its halogenated aromatic structure for bioactivity.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Active Pharmaceutical Ingredient (API) Manufacturing: Incorporated into the final chemical structure of APIs requiring a specific piperazine pharmacophore.
• Ligand and Catalyst Development: Utilized in the creation of specialized ligands for catalysis and metal complexation in fine chemical processes.

Basic Information

Product Name	2-(2,4-Dichloro-5-Fluorophenyl)Piperazine
CAS No.	914348-92-8
Molecular Formula	C10H11Cl2FN2
Molecular Weight	249.11 g/mol
Synonyms	1-(2,4-Dichloro-5-fluorophenyl)piperazine; 2,4-Dichloro-5-fluorophenylpiperazine; 5-Fluoro-2,4-dichlorophenylpiperazine; Piperazine, 1-(2,4-dichloro-5-fluorophenyl)-; (2,4-Dichloro-5-fluorophenyl)piperazine; 914348-92-8; 2,4-Dichloro-5-fluoro-1-piperazin-1-ylbenzene
EINECS	Contact for details

Quality Control

Our 2-(2,4-Dichloro-5-Fluorophenyl)Piperazine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with cGMP, ICH Q7, and other relevant pharmaceutical guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.