Description

1,3-Dioxan-2-One CAS NO 2453-03-4 is a high-purity cyclic carbonate ester, also known as trimethylene carbonate, valued for its role as a key monomer in the synthesis of biodegradable polymers. This compound is essential for creating advanced materials with controlled degradation profiles, making it a cornerstone for sustainable product development. It is primarily sought by manufacturers in the pharmaceutical, biomedical engineering, and specialty plastics industries for applications ranging from drug delivery systems to absorbable medical devices.

Application

• Biodegradable Polymer Synthesis: A primary monomer for producing aliphatic polycarbonates like poly(trimethylene carbonate) (PTMC), used in absorbable sutures, drug-eluting stents, and tissue engineering scaffolds.
• Controlled Drug Delivery Systems: Employed in the fabrication of polymeric microspheres and nanoparticles designed for sustained and targeted release of active pharmaceutical ingredients (APIs).
• Medical Device Manufacturing: Used to create bioresorbable implants, bone fixation devices, and adhesion barriers that safely degrade in the body over time.
• Specialty Adhesives & Coatings: Serves as a building block for high-performance, environmentally friendly coatings and adhesives with specific elasticity and degradation properties.
• Cosmetic & Personal Care Formulations: Incorporated into delivery systems for active ingredients in skincare products, providing enhanced stability and controlled release.
• Academic & Industrial R&D: Utilized as a critical reagent in research for developing new biocompatible and biodegradable polymeric materials.

Basic Information

Product Name	1,3-Dioxan-2-One
CAS No.	2453-03-4
Molecular Formula	C4H6O3
Molecular Weight	102.09 g/mol
Synonyms	Trimethylene Carbonate; 1,3-Dioxan-2-one; TMC; 1,3-Dioxacyclohexan-2-one; Cyclic Trimethylene Carbonate; 2-Oxo-1,3-dioxane; 1,3-Propylene Carbonate (Note: distinct from propylene carbonate); 4-Methyl-1,3-dioxan-2-one (isomer)
EINECS	219-497-3

Quality Control

Our 1,3-Dioxan-2-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for demanding applications like pharmaceutical synthesis. Each lot undergoes rigorous analytical testing, including chromatography and spectroscopy, to confirm identity, potency, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 99.0 %
Melting Point	44 - 48 °C
Water Content (KF)	≤ 0.5 %
Residue on Ignition	≤ 0.1 %
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.