Description

4-(Hydroxymethyl)-5-Methyl-1,3-Dioxol-2-One is a versatile cyclic carbonate derivative, valued for its reactive hydroxymethyl and carbonyl functionalities. This compound serves as a crucial building block and intermediate in the synthesis of more complex molecules, offering a balance of reactivity and stability. It is primarily sought by industries involved in pharmaceutical development, advanced polymer chemistry, and fine chemical manufacturing.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting neurological and metabolic pathways.
• Polymer Modification: Used as a reactive monomer or cross-linking agent to introduce functional groups into polycarbonates, polyurethanes, and other specialty polymers, enhancing properties like biodegradability or adhesion.
• Fine Chemical Synthesis: Serves as a protected glycolaldehyde equivalent or a carbonyl source in multi-step organic synthesis for agrochemicals, dyes, and fragrances.
• Electrolyte Additive: Potential application as an additive in lithium-ion battery electrolytes to improve stability and cycle life.
• Bioconjugation Chemistry: Useful in modifying biomolecules (e.g., peptides, sugars) due to its ability to form stable covalent linkages under mild conditions.
• Cosmetic Ingredient Intermediate: Employed in the production of certain esters or derivatives used in high-end cosmetic formulations.

Basic Information

Product Name	4-(Hydroxymethyl)-5-Methyl-1,3-Dioxol-2-One
CAS No.	91526-18-0
Molecular Formula	C5H6O4
Molecular Weight	130.10 g/mol
Synonyms	5-Methyl-1,3-dioxol-2-one-4-methanol; 4-(Hydroxymethyl)-5-methyl-2-oxo-1,3-dioxolane; 5-Methyl-4-(hydroxymethyl)-1,3-dioxol-2-one; Hydroxymethyl methyl dioxolone; (5-Methyl-2-oxo-1,3-dioxol-4-yl)methanol; Methyl O-carboxyglycolide derivative
EINECS	Contact for details

Quality Control

Our 4-(Hydroxymethyl)-5-Methyl-1,3-Dioxol-2-One is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We can support development projects requiring compliance with ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage, consider using desiccants or storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.