Description

(7S)-7-[[(R)-5-Amino-5-carboxy-1-oxopentyl]amino]-7-methoxy-3-[[[6-amino-3-hydroxy-4-(L-ornithyl-L-valyl-L-ornithyl-L-valylamino)-1,6-dioxohexyl]oxy]methyl]cepham-3-ene-4-carboxylic acid is a complex, semi-synthetic cephalosporin derivative, representing a key advanced intermediate in the synthesis of potent, broad-spectrum antibiotics. Its intricate structure, featuring a cephem core linked to a unique peptide chain, is designed to confer enhanced stability and activity against resistant bacterial strains. This high-value compound is essential for pharmaceutical R&D and manufacturing teams focused on developing next-generation antibacterial therapies.

Application

• Pharmaceutical Intermediate: Primary use as a critical building block in the synthesis of novel cephalosporin antibiotics.
• Antibacterial Drug Development: Serves as a key precursor for research into new agents targeting multi-drug resistant (MDR) bacteria.
• Biochemical Research: Used in studies investigating structure-activity relationships (SAR) and the mechanism of action of β-lactam antibiotics.
• GMP Manufacturing: Supplied as a high-purity intermediate for cGMP-compliant production of active pharmaceutical ingredients (APIs).
• Process Chemistry & Scale-Up: Employed in route scouting, optimization, and pilot-scale synthesis for new antibiotic candidates.

Basic Information

Item	Details
Product Name	(7S)-7-[[(R)-5-Amino-5-carboxy-1-oxopentyl]amino]-7-methoxy-3-[[[6-amino-3-hydroxy-4-(L-ornithyl-L-valyl-L-ornithyl-L-valylamino)-1,6-dioxohexyl]oxy]methyl]cepham-3-ene-4-carboxylic acid
CAS No.	99313-74-3
Molecular Formula	C48H78N12O17
Molecular Weight	1047.2 g/mol
Synonyms	7-Methoxy Cephalosporin Peptide Derivative; Cephem-Peptide Conjugate; (7S)-7-Methoxy-cephalosporin intermediate; Antibiotic Intermediate 99313-74-3; L-Ornithyl-L-valyl-L-ornithyl-L-valyl Cephem Derivative; Advanced Cephalosporin Precursor; Complex β-Lactam Intermediate
EINECS	Contact for details

Quality Control

Our (7S)-7-[[(R)-5-Amino-5-carboxy-1-oxopentyl]amino]-7-methoxy-3-[[[6-amino-3-hydroxy-4-(L-ornithyl-L-valyl-L-ornithyl-L-valylamino)-1,6-dioxohexyl]oxy]methyl]cepham-3-ene-4-carboxylic acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the exacting standards required for pharmaceutical development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccation or storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.