Description

Ceftizoxime is a semi-synthetic, broad-spectrum third-generation cephalosporin antibiotic. It is valued for its potent activity against a wide range of Gram-positive and Gram-negative bacteria, including many β-lactamase-producing strains. This makes it a critical active pharmaceutical ingredient (API) for the formulation of injectable antibiotics used in clinical settings. Key industries requiring this compound include pharmaceutical manufacturing, research and development, and contract synthesis.

Application

• Primary use as an Active Pharmaceutical Ingredient (API) in the manufacture of sterile injectable antibiotic formulations.
• Clinical application for the treatment of serious infections, including respiratory tract infections, urinary tract infections, and intra-abdominal infections.
• Used in veterinary medicine for treating bacterial infections in animals.
• Critical material in pharmaceutical research for studying antibiotic resistance and developing new combination therapies.
• Serves as a reference standard in analytical laboratories for quality control and method development.
• Utilized by contract manufacturing organizations (CMOs) for the production of generic and branded drug products.

Basic Information

Product Name	Ceftizoxime
CAS No.	102044-69-9
Molecular Formula	C13H13N5O5S2
Molecular Weight	383.40 g/mol
Synonyms	Ceftizoxime Sodium; FK-749; FR-13749; (6R,7R)-7-[[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; Ceftizox; Cefizox; Epocelin
EINECS	Contact for details

Quality Control

Our Ceftizoxime is manufactured under strict quality management systems. It undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications, including identification, assay, and impurity profile analysis. Certificates of Analysis (COA) are provided with each batch, detailing compliance with relevant specifications. We can support compliance with USP, EP, and JP monographs as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.2%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%
Bacterial Endotoxins	< 0.10 EU/mg (where applicable)
Sterility	Conforms (for sterile grade)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.