Description

Cephaloridine Monohydrate is a first-generation cephalosporin antibiotic in its monohydrate crystalline form. This compound is valued for its broad-spectrum antibacterial activity, serving as a critical reference standard and active pharmaceutical ingredient (API) in research and development. It is primarily utilized by pharmaceutical manufacturers, analytical laboratories, and research institutions involved in antibiotic development, quality control, and microbiological studies. The product is supplied with full traceability and documentation to support rigorous scientific and regulatory requirements.

Application

• Pharmaceutical Reference Standard: Used for the calibration of analytical instruments, method validation, and quality control testing of cephalosporin-based drugs.
• Active Pharmaceutical Ingredient (API): Serves as a key intermediate or raw material in the formulation of injectable antibiotic preparations.
• Microbiological Research: Employed in in-vitro studies to assess antibacterial efficacy, resistance patterns, and mechanism of action.
• Analytical Chemistry: Essential for developing and verifying HPLC, UV, and other chromatographic assays for cephalosporin quantification.
• Stability Studies: Used as a benchmark in forced degradation and shelf-life determination studies for pharmaceutical products.
• Educational & Clinical Research: Applied in academic settings and clinical trials for pharmacological and pharmacokinetic investigations.

Basic Information

Product Name	Cephaloridine Monohydrate
CAS No.	102039-86-1
Molecular Formula	C19H17N3O4S2 • H2O
Molecular Weight	425.49 g/mol (Monohydrate)
Synonyms	Cephaloridine Hydrate; 7-[(2-Thienylacetyl)amino]-3-(1-pyridylmethyl)-3-cephem-4-carboxylic Acid Betaine Monohydrate; Cefaloridine Monohydrate; Ceporan; Keflodin; Loridine; Cefaloridin; (6R,7R)-7-[(2-thiophen-2-ylacetyl)amino]-3-(pyridin-1-ium-1-ylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate monohydrate
EINECS	Contact for details

Quality Control

Our Cephaloridine Monohydrate is manufactured and tested under strict quality management systems. Each batch is analyzed to meet high-purity standards suitable for pharmaceutical research and development. Comprehensive testing includes identification, assay, impurity profiling, and residual solvent analysis. A Certificate of Analysis (COA) detailing all test results and specifications is provided with every shipment to ensure full transparency and compliance with your quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Water Content (KF)	3.5% - 5.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.