Description

Ceftizoxime CAS NO 68401-81-0 is a semi-synthetic, broad-spectrum cephalosporin antibiotic belonging to the third generation. It is valued for its potent activity against a wide range of Gram-positive and Gram-negative bacteria, including β-lactamase-producing strains. This product is essential for pharmaceutical manufacturers and research institutions developing injectable antibiotic formulations for serious infections.

Application

• Pharmaceutical Active Ingredient (API): Primary use in the formulation of sterile injectable antibiotics.
• Hospital Infection Treatment: Used in drugs targeting severe infections such as pneumonia, septicemia, and complicated urinary tract infections.
• Bacterial Resistance Management: A key agent in combating infections caused by penicillin-resistant organisms.
• Research & Development: Serves as a reference standard and starting material in antimicrobial research and new drug development.
• Veterinary Medicine: Potential application in developing antibacterial treatments for animals.

Basic Information

Product Name	Ceftizoxime
CAS No.	68401-81-0
Molecular Formula	C13H13N5O5S2
Molecular Weight	383.40 g/mol
Synonyms	Ceftizoxime Sodium; FK 749; FR 13749; (6R,7R)-7-[[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid; Ceftizox; Epocelin; Ceftix
EINECS	Contact for details

Quality Control

Our Ceftizoxime is manufactured under strict quality systems. It undergoes comprehensive analytical testing to meet high-purity standards suitable for pharmaceutical applications. A Certificate of Analysis (COA) detailing parameters such as assay, impurities, and microbiological quality is provided with each batch to ensure traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
pH (1% solution)	4.0 - 6.0
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Bacterial Endotoxins	< 0.10 EU/mg
Sterility (where applicable)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.