Description

(2S)-3-(1H-indol-3-yl)-2-[[(2S)-4-methyl-2-[[(2S)-2-[[(2S)-4-methyl-2- [[(2S)-2-[[(2S)-4-methyl-2-(tert-butoxycarbonylamino)pentanoyl]amino]propanoyl]amino]pentanoyl]amino]propanoyl]amino]pentanoyl]amino]propanoic acid is a sophisticated, high-purity synthetic peptide derivative designed for advanced research and development. This compound is a critical building block in the synthesis of complex peptides and peptidomimetics, offering precise stereochemical control for pharmaceutical discovery. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly in the fields of oncology and neurology.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the solid-phase and solution-phase synthesis of targeted peptide-based drug candidates.
• Bioconjugation Research: Used in the development of peptide-drug conjugates (PDCs) and other bioconjugates due to its reactive carboxylic acid and protected amine functionalities.
• Medicinal Chemistry: Acts as a crucial scaffold for structure-activity relationship (SAR) studies to optimize the potency and selectivity of new chemical entities.
• Protease Inhibitor Development: Provides a structural motif relevant for designing inhibitors of specific proteolytic enzymes.
• Biochemical Tool Compound: Employed in biochemical assays to study protein-protein interactions and signal transduction pathways.
• Academic Research: Utilized in university and institutional labs for fundamental studies in peptide chemistry and bioorganic synthesis.

Basic Information

Product Name	(2S)-3-(1H-indol-3-yl)-2-[[(2S)-4-methyl-2-[[(2S)-2-[[(2S)-4-methyl-2- [[(2S)-2-[[(2S)-4-methyl-2-(tert-butoxycarbonylamino)pentanoyl]amino]propanoyl]amino]pentanoyl]amino]propanoyl]amino]pentanoyl]amino]propanoic acid
CAS No.	97399-67-2
Molecular Formula	C43H67N7O10
Molecular Weight	842.04 g/mol
Synonyms	Boc-L-Leu-L-Ala-L-Leu-L-Ala-L-Leu-L-Trp-OH; Boc-Leu-Ala-Leu-Ala-Leu-Trp-OH; (2S)-3-(1H-Indol-3-yl)-2-[(2S)-4-methyl-2-[(2S)-2-[(2S)-4-methyl-2-[(2S)-2-[(2S)-4-methyl-2-[(2-methylpropan-2-yl)oxycarbonylamino]pentanoylamino]propanoylamino]pentanoylamino]propanoylamino]pentanoylamino]propanoic acid; Hexapeptide Boc-Leu-Ala-Leu-Ala-Leu-Trp; N-α-Boc-Leucyl-alanyl-leucyl-alanyl-leucyl-tryptophan
EINECS	Contact for details

Quality Control

Our (2S)-3-(1H-indol-3-yl)-2-[[(2S)-4-methyl-2-[[(2S)-2-[[(2S)-4-methyl-2- [[(2S)-2-[[(2S)-4-methyl-2-(tert-butoxycarbonylamino)pentanoyl]amino]propanoyl]amino]pentanoyl]amino]propanoyl]amino]pentanoyl]amino]propanoic acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, chiral integrity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.