Description

(S)-3-Hydroxy-N,n-Dimethylpyrrolidine-1-Carboxamide CAS NO 1305322-89-7 is a high-purity chiral building block and intermediate of significant interest in advanced organic synthesis. Its value lies in its stereochemically defined pyrrolidine scaffold, which is a privileged structure in medicinal chemistry for modulating biological activity. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, especially in central nervous system (CNS) and metabolic disorder therapeutics.
• Agrochemical Synthesis: Used in the creation of advanced, stereoselective pesticides and herbicides where specific chirality enhances efficacy and reduces environmental impact.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to create enantiomerically pure compounds.
• Academic and R&D Laboratories: A valuable reagent for methodological studies in organic chemistry and for exploring new synthetic pathways.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	(S)-3-Hydroxy-N,n-Dimethylpyrrolidine-1-Carboxamide
CAS No.	1305322-89-7
Molecular Formula	C7H14N2O2
Molecular Weight	158.20 g/mol
Synonyms	(S)-3-Hydroxy-1-(dimethylcarbamoyl)pyrrolidine; (3S)-1-(Dimethylcarbamoyl)pyrrolidin-3-ol; (S)-1-(Dimethylcarbamoyl)-3-hydroxypyrrolidine; (S)-3-Hydroxy-N,N-dimethylpyrrolidine-1-carboxamide; (S)-N,N-Dimethyl-3-hydroxypyrrolidine-1-carboxamide; Pyrrolidine-1-carboxamide, 3-hydroxy-N,N-dimethyl-, (3S)-; (S)-3-Hydroxy-1-(N,N-dimethylaminocarbonyl)pyrrolidine
EINECS	Contact for details

Quality Control

Our (S)-3-Hydroxy-N,n-Dimethylpyrrolidine-1-Carboxamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.