Description

Nipecotamide is a versatile heterocyclic building block and intermediate of significant importance in advanced organic synthesis. Its piperidine-3-carboxamide structure makes it a valuable precursor for the development of active pharmaceutical ingredients (APIs) and fine chemicals. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of various pharmacologically active compounds, including potential central nervous system (CNS) agents and enzyme inhibitors.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its heterocyclic core.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal complexation.
• Fine Chemical Production: Employed in the manufacture of complex, high-value specialty chemicals for various industrial applications.
• Biochemical Research: Utilized as a standard or building block in medicinal chemistry programs and biochemical studies.
• Polymer Modification: Acts as a functional monomer or additive to impart specific properties to polymeric materials.

Basic Information

Product Name	Nipecotamide
CAS No.	4138-26-5
Molecular Formula	C6H12N2O
Molecular Weight	128.17 g/mol
Synonyms	3-Piperidinecarboxamide; Nipecotic acid amide; 3-Carbamoylpiperidine; Piperidine-3-carboxamide; 3-Piperidinecarboxylic acid amide; 3-Aminocarbonylpiperidine; 3-Piperidinecarboxylic acid, amide
EINECS	223-944-5

Quality Control

Our Nipecotamide is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, which include key parameters such as assay, impurity profile, and physical characteristics. Our quality commitment ensures the material meets the stringent requirements for research and cGMP intermediate synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.