Description

Diethyl Acetamidomalonate is a versatile and high-purity organic building block essential for advanced chemical synthesis. Its core value lies in its role as a key precursor for the preparation of unnatural α-amino acids and heterocyclic compounds, enabling the development of novel pharmaceuticals and agrochemicals. This compound is critically needed by research and development laboratories, as well as production facilities in the pharmaceutical, biotechnology, and fine chemical industries seeking to innovate with complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial starting material for the synthesis of non-proteinogenic amino acids used in peptide-based drugs and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Serves as a building block for creating novel herbicides, insecticides, and plant growth regulators with specific biological activity.
• Peptide Mimetics Research: Enables the development of peptide analogs and mimetics for drug discovery programs targeting various diseases.
• Fine Chemical Production: Used in the multi-step synthesis of complex organic molecules for specialty chemicals and material science applications.
• Academic & Industrial R&D: A fundamental reagent in organic chemistry research for methodology development and exploring new synthetic pathways.

Basic Information

Product Name	Diethyl Acetamidomalonate
CAS No.	1068-90-2
Molecular Formula	C9H15NO5
Molecular Weight	217.22 g/mol
Synonyms	Acetamidomalonic Acid Diethyl Ester; Diethyl 2-Acetamidomalonate; Ethyl Acetamidomalonate; Acetamidomalonic Ester; 2-Acetamidomalonic Acid Diethyl Ester; N-Acetylaminomalonic Acid Diethyl Ester; Diethyl (Acetylamino)malonate; Acetamidomalonate Diethyl Ester
EINECS	213-945-3

Quality Control

Our Diethyl Acetamidomalonate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. The product may be hygroscopic; ensure containers are sealed after each use to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	95°C - 99°C
Loss on Drying	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.