Description

(6R,7S)-7α-[[(S)-(2-Amino-4-thiazolyl)[[[(1,4-dihydro-5-hydroxy-4-oxopyridin)-2-yl]carbonyl]amino]acetyl]amino]-8-oxo-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid is a complex, high-purity pharmaceutical intermediate with a defined stereochemistry. This compound is of significant value in the research and development of advanced cephalosporin antibiotics, serving as a key building block for novel active pharmaceutical ingredients (APIs). It is primarily needed by pharmaceutical manufacturers, R&D laboratories, and fine chemical suppliers focused on antibiotic synthesis and process development.

Application

• Key Intermediate for Advanced Cephalosporins: Serves as a critical precursor in the synthesis of next-generation β-lactam antibiotics.
• Pharmaceutical R&D: Used in medicinal chemistry for the development and optimization of new antibacterial agents with improved efficacy and spectrum.
• Process Chemistry & Scale-Up: Employed in pilot plants and manufacturing facilities for route scouting and production process development.
• Reference Standard: Acts as a high-purity analytical standard for quality control and regulatory submissions in API manufacturing.
• Fine Chemical Synthesis: Utilized in custom synthesis and contract manufacturing of specialized, high-value chemical entities.

Basic Information

Product Name	(6R,7S)-7α-[[(S)-(2-Amino-4-thiazolyl)[[[(1,4-dihydro-5-hydroxy-4-oxopyridin)-2-yl]carbonyl]amino]acetyl]amino]-8-oxo-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
CAS No.	93129-06-7
Molecular Formula	C19H18N6O7S
Molecular Weight	474.45 g/mol
Synonyms	7-ACA derivative with thiazole and pyridone side chain; (6R,7S)-7-[(Z)-2-(2-Amino-4-thiazolyl)-2-[[(5-hydroxy-4-oxo-1,4-dihydropyridin-2-yl)carbonyl]amino]acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; Cephalosporin C derivative intermediate; 93129-06-7; 7β-[2-(2-Amino-4-thiazolyl)glyoxylamido]-8-oxo-3-[(1,4-dihydro-5-hydroxy-4-oxo-2-pyridinyl)carbonyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (stereoisomer)
EINECS	Contact for details

Quality Control

Our (6R,7S)-7α-[[(S)-(2-Amino-4-thiazolyl)[[[(1,4-dihydro-5-hydroxy-4-oxopyridin)-2-yl]carbonyl]amino]acetyl]amino]-8-oxo-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity, to ensure it meets the exacting standards required for pharmaceutical intermediate applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% (specified stereoisomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.