Description

7-[(Hydroxyphenylacetyl)amino]-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (5-methyl-2-oxo-1,3-dioxol-4-yl) ester is a complex, semi-synthetic cephalosporin derivative designed for advanced pharmaceutical research and development. This compound is a key chemical intermediate in the synthesis of novel β-lactam antibiotics, offering a sophisticated structural framework for targeting resistant bacterial strains. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing next-generation antimicrobial agents and exploring new mechanisms of action.

Application

• Pharmaceutical Intermediate: Critical building block in the synthesis of advanced-generation cephalosporin antibiotics.
• Antimicrobial Research: Used in R&D for creating novel compounds to combat multi-drug resistant (MDR) bacterial infections.
• Biochemical Studies: Serves as a reference standard or probe in studies of β-lactamase inhibition and bacterial cell wall synthesis.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for specialized pharmaceutical projects.
• Academic Research: Utilized in university and institutional labs for medicinal chemistry and pharmacology programs.

Basic Information

Item	Details
Product Name	7-[(Hydroxyphenylacetyl)amino]-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (5-methyl-2-oxo-1,3-dioxol-4-yl) ester
CAS No.	92114-75-5
Molecular Formula	C24H22N4O8S3
Molecular Weight	590.65 g/mol
Synonyms	Cefmenoxime Ester; Cefmenoxime 1-(2,5-Dioxo-4-oxolanyl)methyl Ester; Cefmenoxime Hemioxalate Ester; (6R,7R)-7-[(2-Hydroxy-2-phenylacetyl)amino]-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 5-methyl-2-oxo-1,3-dioxol-4-ylmethyl ester; SCE-1365 Ester; Antibiotic SCE-1365 Ester
EINECS	Contact for details

Quality Control

Our 7-[(Hydroxyphenylacetyl)amino]-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (5-methyl-2-oxo-1,3-dioxol-4-yl) ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.