Description

1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 3-((2-((3-((2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)amino)-1-oxopropyl)amino)ethyl)thio)-6-(1-hydroxyethyl)-7-oxo-, (5R-(3(R*),5-alpha,6-alpha(S*)))- is a complex, high-purity pharmaceutical intermediate of significant commercial and research interest. This compound is a key building block in the synthesis of advanced β-lactam antibiotics, offering a critical structural motif for developing new therapeutic agents. It is primarily sought after by pharmaceutical manufacturers and research institutions engaged in the development and production of novel antibacterial drugs.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of advanced cephalosporin and carbapenem class antibiotics.
• Antibiotic Research & Development: Used in medicinal chemistry for the design, synthesis, and structure-activity relationship (SAR) studies of new antibacterial compounds.
• Active Pharmaceutical Ingredient (API) Manufacturing: Serves as a key chiral synthon in the commercial-scale production of specific, potent antibiotic APIs.
• Biochemical Research: Employed as a tool compound in studies investigating bacterial cell wall synthesis and the mechanisms of β-lactamase inhibition.
• Process Chemistry Development: Utilized for optimizing synthetic routes and scaling up production processes for complex antibiotic molecules.

Basic Information

Product Name	1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 3-((2-((3-((2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)amino)-1-oxopropyl)amino)ethyl)thio)-6-(1-hydroxyethyl)-7-oxo-, (5R-(3(R*),5-alpha,6-alpha(S*)))-
CAS No.	82475-10-3
Molecular Formula	C20H31N3O8S
Molecular Weight	473.54 g/mol
Synonyms	(5R,6S)-6-[(1R)-1-Hydroxyethyl]-3-({2-[(3-{[(2S,3R)-2,4-Dihydroxy-3,3-dimethyl-1-oxobutyl]amino}-1-oxopropyl)amino]ethyl}thio)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic Acid; 7β-[(2-Amino-2-carboxyethyl)thio]-2-[[(2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)amino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-3-carboxylic Acid Derivative; Cefmenoxime Intermediate; Cefmenoxime Hemihydrochloride Related Compound; Antibiotic Intermediate SC E-070; (5R,6S)-6-[(1R)-1-Hydroxyethyl]-3-[[2-[[(3-[[(2S,3R)-2,4-Dihydroxy-3,3-dimethyl-1-oxobutanoyl]amino]propanoyl)amino]ethyl]thio]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic Acid
EINECS	Contact for details

Quality Control

This high-value pharmaceutical intermediate is manufactured under strict quality management systems to ensure batch-to-batch consistency and purity. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity, potency, and impurity profiles. Certificates of Analysis (COA) detailing all specifications and test results are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and purity. For long-term storage, consider desiccants or inert atmosphere packaging.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.2%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 0.5%
Optical Rotation	Specific range provided on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.